Arne Slot is the first to win the top flight in England where many of his compatriots have suffered dents to their reputations over the years.
Aguero's absence means a likely start for Brazilian Gabriel Jesus in attack.
Liverpool will resume their quest for a first top-flight title in 30 years at city rivals Everton on June 21, as the English Premier League released its revised fixture list for the first three weeks of the restarted season on Friday. Liverpool are 25 points clear at the top and are two victories away from winning the Premier League, but will have a shot at securing the title by beating Everton if City lose to Arsenal.
Manchester United, comprehensively outplayed by local rivals Liverpool and Manchester City at Old Trafford recently, face an even tougher challenge when holders Bayern Munich come calling in the Champions League on Tuesday.
A 19-year-old Manchester United player has been released on bail after several hours of questioning, following an allegation of rape after the soccer team's Christmas party, British media reported on Wednesday.
Manchester City thrashed West Ham United 4-1 in the Premier League on Saturday to claim their first back-to-back wins since October.
'We can work and fight for it' 'Yes, they had much more of the ball. Yes, they had that apparent control of the game but the biggest save is the double save of their goalkeeper and the biggest decision of the game is the unlucky decision of Michael (Oliver)'
The result left the top positions in the Premier League unchanged. Arsenal lead the standings with 47 points, followed by Manchester United (45).
A summary of Sunday's action in the Premier League.
Man United were mistakenly drawn with Villarreal, even though both teams had already faced each other in the group stage.
Manchester City's Sergio Aguero scored from a near-impossible angle to salvage a 2-2 home draw with Liverpool but a memorable Steven Gerrard goal still helped boost Premier League leaders Manchester United on Sunday.
The following is a look back on key moments in the thrilling Premier League title race, won by Manchester City on Sunday:
Arsenal returned to the top of the Premier League with a comfortable 2-0 victory over relegation-threatened Luton Town
The new English season got off to a familiar start as two Sergio Aguero goals, including his 200th for the club, handed Manchester City a 2-0 win over Chelsea and claim the FA Community Shield for the fifth time at a sun-baked Wembley.
Manchester City defender Manuel Akanji said Marcus Rashford was clearly interfering with play in the lead-up to Manchester United's equaliser in their Premier League match on Saturday.
Former BCCI president and batting great Sourav Ganguly on Monday side-stepped the debate surrounding Indian players' refusal to shake hands with their Pakistani counterparts after their Asia Cup clash in Dubai but said terrorism must end "all around the world, not just India and Pakistan."
Manchester United manager Louis van Gaal has poured scorn on critics who he says have made a "devil" of him after one defeat in his new job.
IMAGES from the English Premier League matches played on Wednesday.
IMAGES from the Premier League matches played on Saturday.
Manchester United midfielder Michael Carrick will miss the final three games of the Premier League season with a calf problem, manager Louis van Gaal said on Friday.
The Premier League title race took another dramatic twist on Sunday when leaders Manchester United blew a two-goal lead to draw 4-4 with Everton and Manchester City beat Wolverhampton Wanderers 2-0 to narrow the gap to three points.
Ronaldo had won his first Ballon d'Or in 2008 while he was playing for Manchester United and still holds the record of the last Premier League player to claim the top prize. Messi won his first in 2009 and was nominated for 16 years.
Manchester United showing 'concrete interest' in the French forward
Xherdan Shaqiri inspired StokeCity to a convincing 2-0 victory over Premier League leaders ManchesterCity in blustery conditions at the Britannia Stadium on Saturday.
Manchester City striker Carlos Tevez has branded former Manchester United team-mate Gary Neville a "moron" and accused him of sucking up to his manager Alex Ferguson.
Manchester City and United ground out a tepid 0-0 draw as Michael Essien's goal earned Chelsea a 1-0 victory over Fulham and a four-point cushion at the top of the Premier League on Wednesday.
Brazil, who are fifth in the CONMEBOL table with 18 points from 12 games, host Colombia on March 21 and visit Argentina five days later in a match that could see Neymar come up against former Barcelona and Paris St Germain teammate Lionel Messi.
Saturday's clash between Manchester United and Tottenham Hotspur at Old Trafford is already shaping up as an early-season eliminator to challenge runaway leaders Manchester City for the Premier League title.
With 10 games left, United are now 12 points behind league leaders Arsenal and three behind second-placed Chelsea.
Liverpool were drawn on Thursday to face champions Real Madrid when they return to the Champions League, which has been expanded to a 36-team league format.
Jose Mourinho's delight at Manchester United's progress to the last 16 of the Europa League has been tempered by the timing of their FA Cup quarter-final against Chelsea, with the manager criticising the tie being scheduled for a Monday.
Manchester City seized the chance to put Premier League leaders Manchester United under pressure with David Silva's double in a 2-0 victory over Fulham on Saturday while Liverpool recorded a 5-0 win at home to Norwich City.
'The boys will be pleased not to lose but also definitely not happy we didn't win.'
Manchester City took a huge step towards their first title for 44 years when they won 2-0 at Newcastle United to stay top of the Premier League on goal difference from Manchester United with one match left.
Champions Manchester City climbed to second in the English Premier League table after a Carlos Tevez thunderbolt in the second half gave them a 1-0 win over Swansea City.
Japan, South Korea, Australia, Iran, Uzbekistan and Jordan have already taken six of Asia's eight guaranteed spots at next year's 48-team World Cup.
Manchester United fought back from 2-0 down and struck deep into stoppage time to beat Manchester City 3-2 in a dramatic Community Shield at Wembley on Sunday.
City, storming towards their third league title in four years, scored three late goals to wrap up victory and move onto 65 points with 11 games left to play ahead of Manchester United on 50 points with a game in hand.
Manchester United climbed to third place in their quest for a berth in next season's Champions League.
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